SAN ANTONIO — A new study from the University of Texas Health Science Center shows Hipanics in South Texas aren’t living as healthy a lifestyle. It shows almost 38 percent of them are obese.
“This may well be the first generation that does not outlive their parents,” said UTHSC researcher Dorothy Long Parma. “The reason is that obesity is linked to many, many cancers. Many cancers are being found in as young an age as preschoolers.” Read more
Objectives. We assessed whether community health workers (CHWs) could improve glycemic control among Mexican Americans with diabetes.
Methods. We recruited 144 Mexican Americans with type 2 diabetes between January 2006 and September 2008 into the single-blinded, randomized controlled Mexican American Trial of Community Health Workers (MATCH) and followed them for 2 years. Participants were assigned to either a CHW intervention, delivering self-management training through 36 home visits over 2 years, or a bilingual control newsletter delivering the same information on the same schedule. Read More
Purpose. It is unclear whether sociocultural and socioeconomic factors are directly linked to type 2 diabetes risk in overweight/obese ethnic minority children and adolescents. This study examines the relationships between sociocultural orientation, household social position, and type 2 diabetes risk in overweight/obese African-American () and Latino-American () children and adolescents.Methods. Sociocultural orientation was assessed using the Acculturation, Habits, and Interests Multicultural Scale for Adolescents (AHIMSA) questionnaire. Household social position was calculated using the Hollingshead Two-Factor Index of Social Position. Insulin sensitivity (SI), acute insulin response (AIRG) and disposition index (DI) were derived from a frequently sampled intravenous glucose tolerance test (FSIGT). The relationships between AHIMSA subscales (i.e., integration, assimilation, separation, and marginalization), household social position and FSIGT parameters were assessed using multiple linear regression. Read more
OBJECTIVE Insulin receptor substrate 1 (IRS1) is central to insulin signaling pathways. This study aimed to examine the association of IRS1 variants with insulin resistance (IR) and related phenotypes, as well as potential modification by diet.
RESEARCH DESIGN AND METHODS Two IRS1 variants (rs7578326 and rs2943641) identified by genome-wide association studies as related to type 2 diabetes were tested for their associations with IR and related traits and interaction with diet in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) study (n = 820) and the Boston Puerto Rican Health Study (BPRHS) (n = 844). Read more
Sometimes, all the latest headlines on steps towards curing diabetes can seem like a broken record — just researchers crying wolf about how big and bad their science projects are.
Fellow type 1 Lisa Hepner in California gets that, and as someone living with diabetes for more than 20 years, she often agrees. But the progress in the past few years involving islet cell transplantation and encapsulation still gives her hopeful goose bumps, and that hopeful feeling is what’s behind the feature documentary she’s creating about the research race to find a cure, The Human Trial, which she’s filming with her husband, Guy Mossman.
She knows these projects don’t always produce the desired results, but hopes her film will make type 1 is better understood and recognized as a condition that needs more funding and public attention. Read More
Context: Rabson-Mendenhall syndrome (RMS) is caused by mutations of the insulin receptor, and results in extreme insulin resistance and dysglycemia. Hyperglycemia in RMS is very difficult to treat, and patients are at risk for early morbidity and mortality from complications of diabetes.
Objective: To study one year effects of recombinant human methionyl leptin (metreleptin) in five patients with RMS, and ten year effects in two of these patients. Read more
Before the landmark Diabetes Control and Complications Trial (DCCT), Carolyn Wolf was not a huge fan of diabetes dos and don’ts. “At that time, they gave us only so many calories. I could be compliant with injections, but staying to a particular calorie allotment was difficult,” she says. “I felt like I was in prison when I was on that type of therapy.”
While studying to become a dietitian, Wolf had an internship at a hospital. “I saw firsthand people with long-term complications,” she says. “It was very frightening to me.” Wolf wanted to do everything she could to avoid that fate.
After reading an ad in a Detroit newspaper, Wolf thought DCCT could give her an edge against diabetes. “I was really jazzed to be in a research study,” she says. “It was a perfect way to learn how to take care of my diabetes. Plus, if this study proved to be something good, I could benefit other people with diabetes in the future.” Read More
The
South Texas Diabetes Initiative, a program of the Minority Diabetes Coalition,
is sponsored by Boehringer Ingelheim, Roche Diagnostics
and Eli Lilly.
