Association of Depression With Accelerated Cognitive Decline Among Patients With Type 2 Diabetes in the ACCORD-MIND Trial

JAMA: 8/14/13

Importance   Depression has been identified as a risk factor for dementia among patients with type 2 diabetes mellitus but the cognitive domains and patient groups most affected have not been identified.

Objective   To determine whether comorbid depression in patients with type 2 diabetes accelerates cognitive decline.

Design   A 40-month cohort study of participants in the Action to Control Cardiovascular Risk in Diabetes–Memory in Diabetes (ACCORD-MIND) trial.

Setting   Fifty-two clinics organized into 6 clinical networks across the United States and Canada.

Participants   Two thousand nine hundred seventy-seven participants with type 2 diabetes at high risk for cardiovascular events. Read more

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