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Thursday, June 27th, 2013
MedPage Today
Newly diagnosed type 2 diabetes patients are less likely to follow their medication regimen than those with longer-standing disease, and those who take more pills are more likely to be adherent than those on fewer medications, a study found.
The odds of having prescriptions filled at least 80% of the time were 61% lower for patients new to diabetes treatment, and were 5% higher the more pills in the regimen (both P<0.001), Ronald Aubert, PhD, MSPH, then of the pharmacy benefits management company Express Scripts, and colleagues found in an analysis of Medicare beneficiary claims.
Further proof that number of pills may not effect medication adherence came from another survey conducted online by A. Bret Hauber, PhD, of the pharmaceutical research firm RTI Health Solutions in Research Triangle Park, N.C., and colleagues. Read more
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Thursday, June 27th, 2013
Diabetes Care June 25, 2013
OBJECTIVE This study compared the clinical and economic benefits associated with dual-goal achievement, glycated hemoglobin (HbA1c) <7% (53 mmol/mol) and LDL cholesterol (LDL-C) <100 mg/dL, with achievement of only the LDL-C goal or only the HbA1c goal in veterans with type 2 diabetes mellitus (T2DM).
RESEARCH DESIGN AND METHODS This retrospective cohort analysis evaluated electronic medical records (Veterans Integrated Service Network 16) in adult T2DM patients with two or more measurements of LDL-C and HbA1c between 1 January 2004 and 30 June 2010 (N = 75,646). Cox proportional hazards models were used to compare microvascular and cardiovascular outcomes by goal achievement status; generalized linear regression models were used to assess diabetes-related resource utilization (hospitalization days and number of outpatient visits) and medical service costs. Read more
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Thursday, June 27th, 2013
ADA June 20, 2013
The epidemic growth of type 2 diabetes in the U.S. over the past decade has clearly been shown to be associated with social, environmental and economic factors, as outlined in a Scientific Statement released today by the American Diabetes Association at its 73rd Scientific Sessions®. The release of the statement coincides with a call for research applications to target these socioecological factors in a rigorous scientific manner, so that programs may be developed that would strive to prevent diabetes through community-based interventions
The statement notes that “current prevalence rates are staggering” for both obesity and type 2 diabetes, “and are expected to continue to climb over the ensuing decades.” One-third of adults and up to 18 percent of youth are obese, while one in three Americans are expected to develop type 2 diabetes by the year 2050 if current trends continue. Currently, 8.3 percent of the U.S. population lives with diabetes and an additional 35 percent have prediabetes, putting them at high risk for developing type 2 diabetes. Read more
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Thursday, June 27th, 2013
The Diabetes Educator June 19, 2013
Purpose The purpose of this study was to explore the level of physical activity, barriers to physical activity, and strategies used to meet physical activity goals in people with type 2 diabetes (T2DM).
Methods A descriptive, cross-sectional design was used in a sample of 75 adults with T2DM enrolled in a worksite diabetes disease management program (WDDMP). Participants self-reported the length of time they engaged in moderate-intensity physical activity, the frequency of general and specific physical activity, and barriers to participating in physical activity. Read more
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Thursday, June 27th, 2013
Diabetes Care January 24, 2013
OBJECTIVE Carbohydrate nutrition during periods of physiological insulin resistance such as puberty may affect future risk of type 2 diabetes. This study examined whether the amount or the quality (dietary glycemic index [GI], glycemic load [GL], and added sugar, fiber, and whole-grain intake) of carbohydrates during puberty is associated with risk markers of type 2 diabetes in younger adulthood.
RESEARCH DESIGN AND METHODS The analysis was based on 226 participants (121 girls and 105 boys) from the Dortmund Nutritional and Anthropometric Longitudinally Designed Study (DONALD) with an average of five 3-day weighed dietary records (range 2–6) during puberty (girls, age 9–14 years; boys, age 10–15 years) and fasting blood samples in younger adulthood (age 18–36 years) (average duration of follow-up 12.6 years). Read more
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Minority Diabetes Reports
Thursday, June 27th, 2013
Diabetes Care July 1, 2013
Diabetes incidence can be reduced by lifestyle interventions aimed at weight loss, diet change, and increased physical activity, according to several randomized clinical trials (RCTs) (1–5). Similarly, diabetes incidence rates were reduced in RCTs of metformin, acarbose, troglitazone, rosiglitazone, and pioglitazone (1,4,6–9). These RCTs enrolled nondiabetic adults who were at high risk of developing type 2 diabetes by virtue of having one of more of these characteristics: overweight or obesity, elevated fasting glucose, and impaired glucose tolerance in an oral glucose tolerance test. These lifestyle or drug interventions reduced diabetes incidence rates substantially, with risk reductions ranging from about 25–75%. Diabetes incidence was reduced by 58% during the 2.8-year initial phase of the largest such lifestyle intervention trial, the U.S. Diabetes Prevention Program (DPP) (1). This occurred among all the major race/ethnic groups in the DPP, including American Indians. Read more
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Minority Diabetes Reports
Thursday, June 27th, 2013
Clinical Endocrinology News June 24, 2013
Results from a large, ongoing epidemiologic study demonstrated a positive association between African ancestry and fasting glucose in individuals without diagnosed diabetes.
“This association is not substantively diminished by accounting for body mass index or available socioeconomic status measures, suggesting that differences between African Americans and whites in diabetes risk might include genetic/biologically mediated differences in glucose homeostasis,” Dr. James B. Meigs reported at the annual scientific sessions of the American Diabetes Association.
Dr. Meigs, who directs the Massachusetts General Hospital Clinical Research Program’s Disease Management Research Unit, presented findings from 1,545 individuals without diagnosed diabetes who are enrolled in the Boston Area Community Health (BACH) Pre-Diabetes Study, an ongoing, community-based, random-sample cohort study. During morning in-home interviews, the researchers collected data on body mass index and socioeconomic status, and took samples for analysis of fasting glucose and DNA for genotyping 63 markers that discriminate between European, African, and Native American ancestry. Read more
