Screening Tests for Gestational Diabetes: A Systematic Review for the U.S. Preventive Services Task Force

Ann Intern Medicine: May 28, 2013

Background: A 50-g oral glucose challenge test (OGCT) is a widely accepted screening test for gestational diabetes mellitus (GDM), but other options are being considered.

Purpose: To systematically review the test characteristics of various screening methods for GDM across a range of recommended diagnostic glucose thresholds.

Data Sources: 15 electronic databases from 1995 to May 2012, reference lists, Web sites of relevant organizations, and gray literature.

Study Selection: Two reviewers independently identified English-language prospective studies that compared any screening test for GDM with any reference standard.

Data Extraction: One reviewer extracted and a second reviewer verified data from 51 cohort studies. Two reviewers independently assessed methodological quality.  Read more