Posted by Staff
News
Tuesday, May 29th, 2012
Media.aace.com: Saturday, May 26, 2012 8:10 am EDT.
PHILADELPHIA–(BUSINESS WIRE)–Pre-diabetic patients who engage in regular aerobic exercise improve their vascular reactivity to nearly normal levels, even if no weight loss is achieved, according to research presented today at the American Association of Clinical Endocrinologists (AACE) 21st Annual Meeting & Clinical Congress in Philadelphia. Pre-diabetes is a condition that affects nearly one in every four Americans.
The research included patients at-risk of developing diabetes and studied their vascular reactivity, which is associated with heart disease, in relation to exercise. Those persons who exercised at least 150 minutes per week had vascular reactivity near normal levels of a non-diabetic person, in addition to experiencing significant reductions in cholesterol profiles and markers of inflammation, which have been associated with heart attacks. Interestingly, the patients undertaking exercise did not lose weight during the six-week intervention period, indicating the improvement in vascular reactivity was independent of weight loss.
“Knowing that exercise significantly improves vascular reactivity for pre-diabetic patients is substantial,” said Dr. Sabyasachi Sen, MD, MRCP, FACP, lead author on the study. “It appears that the pre-diabetic stage is a therapeutic window when aerobic exercise can make significant improvement in vascular reactivity and bring it back towards normalcy, before these patients progress to overt diabetes. It may be too late in the overt diabetes stage to make significant impact in vascular reactivity with exercise alone.” Read more
Posted by Staff
News
Tuesday, May 29th, 2012
Datadesigndiabetes.com: 5/24/2012.
The two finalists were chosen by our expert panel of judges. The judges considered feedback gathered during the open voting period, and selected the finalists based on their collective evaluation of the strength of each concept, efficacy of prototype, scalability of solution, and team performance during the Demo Day that took place on May 16th at Blueprint Health, a health tech startup incubator in New York City.
This year’s semi-finalists presented an impressive group of solutions to improve diabetes care, and we thank all the teams for their continued dedication to helping people living with diabetes. It certainly wasn’t easy for the judges to select this year’s finalists from such an outstanding group.
As finalists of the 2012 Data Design Diabetes Innovation Challenge, n4a Diabetes Care Center and EnduringFX will receive an additional $10,000 each to test their prototypes within a community of people living with diabetes.
The community uptake stage fosters a dialogue with people living with diabetes, and highlights the importance of building human-centered healthcare solutions. Following this final stage of the Innovation Challenge, the judges will evaluate how each finalist’s concept was received by people living with diabetes, and how the finalists responded and adapted their concepts based on the feedback they gathered.
DYNAMIC DATABASE+FEEDBACK SYSTEM
Sensor-driven system coupled with heart rate monitoring promotes physical activity as a means to improve blood glucose control.
“EnduringFX represents a potential to completely disrupt the typical approach to health, wellness, and chronic disease management like diabetes by mashing up advanced technology and data with social activity grounded in a person’s local community.”
Dennis Urbaniak, Sanofi US
“Recognition of environmental medicine as an important component of prevention and intervention is stellar.”
Ilene Klein, Qualcomm Life
PREDICTIVE ANALYSIS SYSTEM
Matches patients with certain cost patterns and risk profiles to appropriate support and services designed to slow the progression and expenditures of the disease.
“n4a Diabetes Care Center has the kernel of something that could be quite tremendous.” Jon Brilliant, WellDoc
“As a big data person, I loved the predictive data analyses of this solution.”
Lesa Mitchell, Kauffman Foundation Read More
Posted by Staff
News
Tuesday, May 29th, 2012
Cdc.gov: 5/14/2012.
If you are a woman with diabetes, you still can have a healthy baby. Talk with your doctor about whether it is safe for you to become pregnant. Ask your doctor what you need to do before you get pregnant, how to prevent pregnancy while you are getting your blood sugar under control, and how to keep your blood sugar under tight control both before and during your pregnancy. If you find that you are pregnant before your blood sugar in control, the best way to care for your baby is to start now to control your blood sugar. Talk with your doctor to learn how.
Controlling your diabetes before and during your pregnancy will help prevent such problems as birth defects, prematurity, miscarriage, and stillbirth. Read more
Posted by Staff
News
Tuesday, May 29th, 2012
Care.diabetesjournals.org: 4/26/2012.
OBJECTIVE We used a mixed-methods approach to explore the relationships between participants’ perceptions of family members’ diabetes self-care knowledge, family members’ diabetes-specific supportive and nonsupportive behaviors, and participants’ medication adherence and glycemic control (A1C).
RESEARCH DESIGN AND METHODS Adults with type 2 diabetes participated in focus group sessions that discussed barriers and facilitators to diabetes management (n = 45) and/or completed surveys (n = 61) to collect demographic information, measures of diabetes medication adherence, perceptions of family members’ diabetes self-care knowledge, and perceptions of family members’ diabetes-specific supportive and nonsupportive behaviors. Most recent A1C was extracted from the medical record. Read more
Posted by Staff
News
Tuesday, May 29th, 2012
Care.diabetesjournals.org: 4/3/2012.
OBJECTIVE The association between quantity of fruit and vegetable (F&V) intake and risk of type 2 diabetes (T2D) is not clear, and the relationship with variety of intake is unknown. The current study examined the association of both quantity and variety of F&V intake and risk of T2D.
RESEARCH DESIGN AND METHODS We examined the 11-year incidence of T2D in relation to quantity and variety of fruit, vegetables, and combined F&V intake in a case-cohort study of 3,704 participants (n = 653 diabetes cases) nested within the European Prospective Investigation into Cancer and Nutrition-Norfolk study, who completed 7-day prospective food diaries. Variety of intake was derived from the total number of different items consumed in a 1-week period. Multivariable, Prentice-weighted Cox regression was used to estimate hazard ratios (HRs) and 95% CIs. Read more
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Minority Diabetes Reports
Tuesday, May 29th, 2012
Census.gov: THURSDAY, MAY 24, 2012.
The Census Bureau today released new detailed estimates about the social, economic and housing characteristics of hundreds of race, tribal, Hispanic and ancestry groups at numerous geographic levels. This is the first time this level of statistical detail has been available for groups since the 2000 Census. The new products, based on the 2006-2010 American Community Survey (ACS), are generally comparable to estimates generated from the 2000 Census “long form.”
Estimates are available for groups that meet a size threshold and for geographic areas that meet a completed survey response threshold. Up to 300 tables are included on topics such as educational attainment, fertility, nativity, citizenship, income, poverty and homeownership. Read more
Posted by Staff
Minority Diabetes Reports
Tuesday, May 29th, 2012
Diabetes.diabetesjournals.org: 4/3/2012
Protein tyrosine phosphatase 1B (PTP1B) is postulated to modulate insulin action by dephosphorylating the insulin receptor signaling proteins and attenuating insulin signaling. We sought to determine the relationship of skeletal muscle PTP1B to whole-body insulin sensitivity. We studied 17 African Americans with type 2 diabetes mellitus (T2DM) and 16 without diabetes. PTP1B gene expression and protein abundance were determined in the biopsied skeletal muscles at the baseline of a hyperinsulinemic-euglycemic clamp. PTP1B gene expression was significantly higher in subjects with T2DM versus control (P < 0.0001) and remained significantly different after adjusting for age and insulin sensitivity (P = 0.05). PTP1B gene expression was positively related to protein abundance (rs = 0.39; P = 0.03; adjusted for age and insulin sensitivity) and negatively related to insulin sensitivity (rs = −0.52; P = 0.002; adjusted for age). Overexpression and interference RNA of PTP1B were performed in primary human skeletal muscle culture. PTP1B overexpression resulted in reduction of Akt phosphorylation in the control subjects. Read more
