Obesity, Type 2 Diabetes Mellitus, and Other Comorbidities

Archsurg.ama-assn.org: April 16, 2012.

A Prospective Cohort Study of Laparoscopic Sleeve Gastrectomy vs Medical Treatment

Frida Leonetti, MD, PhD; Danila Capoccia, MD; Federica Coccia, MD; Giovanni Casella, MD; Giovanni Baglio, MD, MSc; Francesca Paradiso, MD;Francesca Abbatini, MD; Angelo Iossa, MD; Emanuele Soricelli, MD; Nicola Basso, MD 

Arch Surg. Published online April 16, 2012. doi:10.1001/archsurg.2012.222

Objective  To compare the effect of sleeve gastrectomy vs medical therapy on type 2 diabetes mellitus and other obesity-related comorbidities (obstructive sleep apnea syndrome, hypertension, and dyslipidemia) in prospectively enrolled and matched obese patients with type 2 diabetes.

Design  A prospective cohort study. Morbidly obese patients with type 2 diabetes who either underwent sleeve gastrectomy or conventional therapy were followed up and assessed for their diabetic state and other comorbidities every 3 months for 18 months.

Setting  Centre for the Surgical-Medical Treatment of Morbid Obesity, Policlinico “Umberto I,” University of Rome “Sapienza,” Italy.

Patients  A total of 30 morbidly obese patients with type 2 diabetes who underwent sleeve gastrectomy (group A) and a total of 30 morbidly obese patients with type 2 diabetes who underwent conventional therapy (group B). Read More